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A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

The central nervous system (CNS) is considered an organ devoid of lymphatic vasculature.
Yet, part of the cerebrospinal fluid (CSF) drains into the cervical lymph nodes (LNs). The
mechanism of CSF entry into the LNs has been unclear. Here we report the surprising
finding of a lymphatic vessel network in the dura mater of the mouse brain.