Different molecular complexes that mediate transcriptional induction and repression by FoxP3
The transcription factor FoxP3 is endowed with the ability to repress conventional T cell phenotype while promoting Treg immunoregulatory properties by binding several specific sequences on the genome of T lymphocytes. However, understanding the mechanism by which this myriad of signals is coordinated in Tregs is no easy task, partly due to the fact that […]