In neurodegeneration, grey matters: β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration

Experimental autoimmune encephalomyelitis (EAE) is quite possibly the most widely used animal model for multiple sclerosis (MS) and has shed light on several immunopathogenic processes that lead to this disease. On the other hand, grey matter degeneration -a crucial hallmark of the human MS- has always represented an elusive element in this model as EAE […]