The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease
Aryl hydrocarbon receptor (AHR) is a pivotal protein that belongs to PAS [PER (periodic circadian protein)-ARNT(AHR nuclear translocator)-SIM (single-minded protein)] domain-containing receptor superfamily. This group of proteins play a central role in regulating cellular homeostasis by sensing endogenous (e.g. redox status and oxygen partial pressure) and exogenous stimuli (e.g. toxic aromatic hydrocarbons), and AHR, in […]