B cell depletion therapy does not resolve chronic active multiple sclerosis lesions
Chronic active lesions (CAL), a neuropathological finding of multiple sclerosis (MS), are a very important predictors of severity and progression of the disease, including progression independent of relapse activity (PIRA). In the other hand, a possibility to study “in vivo” the CAL is the evaluation of paramagnetic rim lesions (PRL) which can be detected using […]