Lymphotoxin-alpha expression in the meninges causes lymphoid tissue formation and neurodegeneration

The progressive stage of multiple sclerosis (MS) has been suggested to be related to the central nervous system compartmentalization of the inflammation. Bates et Al. have been investigated the role of leptomeningeal inflammation in driving cortical pathology, focusing on the lymphotoxin (LTα) pathways that are known to play a key role in organogenesis and maintenance […]