Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination
Das Neves SP et al. demonstrated that dysfunction of the meningeal lymphatics leads to the loss of mature oligodendrocytes and subsequent demyelination in the brain. Defective meningeal lymphatics create a neuroinflammatory environment that hinders the replenishment of oligodendrocytes following a demyelinating injury. Interestingly, in patients with multiple sclerosis, a decrease in vascular endothelial growth factor […]