Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells

NMDAR encephalitis is characterized by the presence of specific autoantibodies that specifically target the NMDAR channel and have been shown to be pathogenic in various in vitro and in vivo models. Reincke et Al. developed a CAAR NMDAR which permit to eliminate selective B cells that produce NMDAR autoantibodies. In detail, they developed a CAAR […]