Mitochondrial complex I activity in microglia sustains neuroinflammation
The smoldering inflammation is a hallmark of the progressive phase of multiple sclerosis. In this cutting-edge paper Peruzzotti-Jametti et Al. investigated the mechanism underlying sustained activation of myeloid cells in multiple sclerosis (MS), demonstrating that: Overall, this work is extremely relevant because it has shown that the mitochondrial complex I could be a future therapeutic […]