Jens Kuhle

Head Multiple Sclerosis Centre and Neuroimmunology Unit
Department of Neurology | Clinical Neuroimmunology
Departments of Biomedicine and Clinical Research
University and University Hospital Basel
Basel | Switzerland

Jens Kuhle obtained his MD in Tübingen, Germany and specialised in neurology and neuroimmunology at the University Hospital Basel.

After his PhD in Neuroimmunology at Queen Mary University in London (2012-2014) in the laboratory of Gavin Giovannoni, he returned to Basel as research group leader in the Clinical Neuroimmunology unit in the Department of Clinical Research and Biomedicine, and became Deputy Head of Outpatient Clinic and MS Centre, University Hospital Basel.

Since 2018 he is Associate Professor and Head of Multiple Sclerosis Center and was appointed as Head of the Neuroimmunology Unit in 2021.

His research work in the field of translational medicine focuses on the development of fluid biomarkers, e.g. neurofilament light chain (NfL) in MS, and other neurological disease, establishing NfL as the first blood-based biofluid marker validated for use in personalised medicine.

He is the initiator and Principal Investigator of the Swiss MS Cohort (SMSC) that has developed since its foundation in 2012 to one of the largest biobanks and clinical and imaging information resources worldwide with now more than 2000 patients followed longitudinally. The SMSC serves as a platform for biomarker discovery and development, clinical outcome research and pragmatic trailing in MS in national and international research projects.

Jens’ research is supported by the Swiss National science foundation, the Swiss MS Society and the International Progressive MS Alliance; he authored more than 350 scientific publications and has been named as ‘Highly Cited Researcher’ in 2022, 2023 and 2024.