Auto-antibodies mediated diseases in neurology “Merenda sinojra”
Chairs: Sara Mariotto (University of Verona – Verona, Italy) & Eleonora Virgilio (University of Torino – Turin, Italy)
14:30-15:00 Detection and functional characterization of autoantibodies against neuronal proteins Jakob Kreye (Charité University Medicine – Berlin, Germany)
15:00-15:30 Antibody targets against glial surface proteins in demyelinating disorders Matteo Gastaldi (IRCCS Mondino Foundation & University of Pavia – Pavia, Italy)
15:30-16:00 Pathogenic mechanism in MUSK myasthenia and other IgG4 related disorders Maartje G Huijbers (Leiden University Medical Center – Leiden, the Netherlands)
Oral Presentations 16:00-16:12 703 | Extensive characterization of HSV1 antibody responses in herpes encephalitis reveals compartmentalization in CSF and predicts development of post-herpes autoimmune encephalitis Marianna Spatola (University of Barcelona, Spain and Caixa Research Institute (CRI) – Barcelona, Spain)
16:12-16:24 714 | Identification of a Novel Metabolically Active B Cell Cluster in Refractory Myasthenia Gravis: Insights into Plasma Cell Precursors and Therapy Resistance Biomarkers Jacopo Morroni (Fondazione Policlinico Universitario “A. Gemelli” IRCCS – Rome, Italy)
16:24-16:36 744 | Complement factor C5a, and granulocyte and astrocyte markers in CSF associate with disability in myelin oligodendrocyte glycoprotein antibody-associated disease and neuromyelitis optica spectrum disorder, and differentiate in acute stages versus MS David Leppert (University Hospital and University of Basel – Basel, Switzerland)
16:36-17:48 773 | Serological quantitative, qualitative and functional profiling and neurofilaments as biomarkers in autoimmune encephalitis with LGI1 and CASPR2 antibodies Pietro Businaro (University of Pavia – Pavia, Italy)
17:48-17:00 723 | FcRn Inhibition by Efgartigimod in Myasthenia Gravis: evidence for immunoregulatory effects beyond IgG reduction Maria Cristina Tarasco (Fondazione IRCCS Istituto Neurologico Carlo Besta – Milan, Italy/ University of Milano-Bicocca – Monza, Italy)
