Chairs: Martina Severa (ISS – Rome, Italy) & Claudio Procaccini (EOS-CNR – Naples, Italy) & Rosella Mechelli (IRCCS San Raffaele – Rome, Italy)
706 | Choroid plexus involvement in progressive multiple sclerosis: insights from neuropathology and CSF analysis
Marina Mastantuono (University of Verona – Verona, Italy)
711 | A Combined Biomarker Panel Reflecting Immune Activation and Axonal Damage for Stratifying Early Multiple Sclerosis Patients at Risk of Progression
Maria Ilenia De Bartolo (Sapienza University of Rome – Rome, Italy/IRCCS Neuromed – Pozzilli, Italy)
712 | Exploring neurofilaments heavy chains (NfH) as a potential biomarker of disease progression in multiple sclerosis: A Multimodal analysis
Elena Barusolo (University of Verona – Verona, Italy)
715 | Specialized Pro-resolving lipid Mediators modulate choroid plexus inflammatory activity in Multiple Sclerosis
Veronica Ceci (IFT-CNR/IRCCS Santa Lucia Foundation – Rome, Italy)
716 | Altered hematopoiesis in the skull bone marrow in a mouse model of Parkinson’s disease
Marta Bottero (Dipartimento di Meidicna Sperimentale (DIMES) – Genoa, Italy)
717 | Rubik: a fluorescent reporter to label and manipulate specific neuronal populations in neurological disorders
Giada Pessina (University of Genoa – Genoa, Italy)
718 | tDCS promotes myelin repair and plasticity in the mouse motor cortex
Enrica Boda (University of Turin – Turin, Italy)
719 | Identifying predictors of response in Multiple Sclerosis subjects treated with anti-CD20: ocrelizumab overcomes FcγRIIIA-V158F–associated resistance
Davide Mele (University of Campania “Luigi Vanvitelli” – Naples, Italy)
722 | Maresin-1 promotes neuroprotection and modulates inflammatory responses in preclinical models of multiple sclerosis.
Giulia Carrera (IRCCS Santa Lucia Foundation/University of Rome Tor Vergata – Rome, Italy)
724 | MiR-150-5p and miR-146a-5p as biomarkers for monitoring patient-specific response to innovative targeted therapies in Myasthenia Gravis
Alessia Berni (Fondazione IRCCS Istituto Neurologico Carlo Besta – Milan, Italy)
733 | Alemtuzumab, but not ocrelizumab, induces complement-dependent cytotoxicity and increases sterile inflammatory markers in people with multiple sclerosis
Giada Maria Giunta (Fondazione IRCCS Istituto Neurologico Carlo Besta – Milan, Italy)
735 | Quantitative Analysis of AQP4 and MOG Antibodies Titres: Correlation with Relapses
Martina Nasello (University of Oxford – Oxford, UK/Sapienza University of Rome – Rome, Italy)
736 | Periprandial high fat diet feeding impacts the blood count of neutrophils via cholinergic receptor nicotinic alpha 7 activation
Giovanni Battista Vingiani (University of Milan – Milan, Italy)
737 | Establishing Stable Acetylcholine Receptor Expression in RD Cells Using the PiggyBac System: Improving Platforms for Functional Assays
Veronica Morcone (Università Cattolica del Sacro Cuore – Rome, Italy)
739 | First demyelinating attack in children: a single-center experience
Alessandro Santagostino Barbone (University of Genova – Genoa, Italy)
740 | Phenotypical analysis of innate immune system in neuropathy by antibodies anti-myelin associated glycoprotein
Anastasia Lechiara (IRCCS Ospedale Policlinico San Martino – Genoa, Italy)
742 | The role of irisin in regulating inflammasome-mediated neuroinflammation in Ab42-stimulated 3D or 2D human microglial cell lines
Marina Saresella (IRCCS Fondazione Don Carlo Gnocchi – Milan, Italy)
746 | Upregulation of the transcriptional repressor REST/NRSF as a protective mechanism against neuroinflammation in a mouse model of Multiple Sclerosis
Giorgio Grasselli (IRCCS Ospedale Policlinico San Martino/Italian Institute of Technology/University of Genoa – Genoa, Italy)
754 | Unraveling the inflammation–degeneration tangle in early MS: insights from ferritin, neurogranin, TREM2 and retinal ganglion cell layer
Annamaria Greco (University of Foggia – Foggia, Italy)
759 | Targeting astrocyte CTR1 to promote tissue homeostasis under CNS neuroinflammation
Emanuela Colombo (IRCCS San Raffaele Hospital – Milan, Italy)
760 | Activation of Somatostatin-Expressing AgRP Neurons contribute to the pathogenesis of experimental autoimmune encephalomyelitis
Eleonora Cornacchia (University of Genoa – Genoa, Italy)
761 | Deep Spatial Phenotyping of Microglia in Human Alzheimer’s Disease Brain Tissue
Dusan Zencak (Akoya Biosciences – Marlbourough, MA, USA)
763 | Comparison between technologies and biological approaches for CSF and serum NFL quantification: a further step towards implementation in clinical practice
Cecilia Irene Bava (A.O.U. San Luigi Gonzaga – Orbassano, Italy)
764 | sNFL as additional biomarker for clinical management of multiple sclerosis
Lucia Giorgi (San Luigi Gonzaga University Hospital – Orbassano, Italy)
765 | BB-CRESM: a structured institutional biobank for quality research in Multiple Sclerosis
Lucia Giorgi (Neuroscience Institute Cavalieri Ottolenghi (NICO) – Orbassano, Italy)
767 | ANTI-INFLAMMATORY PROPERTIES OF PLANT-DERIVED BIOACTIVE MOLECULES IN NEUROINFLAMMATORY AND NEURODEGENERATIVE DISEASES
Pallab Majumder (University of Verona – Verona, Italy)
772 | INTERLEUKIN-9 REDUCES INTERLEUKIN-1B-MEDIATED NF-kB ACTIVATION IN HUMAN MACROPHAGES AND MICROGLIA.
Simona Mazzella di Regnella (IRCSS Fondazione Santa Lucia – Rome, Italy)
777 | Inhibition of peptidylarginine deiminases reduces cognitive decline and alleviates neuropathological changes in a mouse model of Alzheimer’s disease
Enrica Caterina Pietronigro (University of Verona – Verona, Italy)
778 | Organotypic brain and spinal cord slice cultures as a novel approach for investigating neuroinflammation and neurotoxicity
Antonella Calore (University of Verona – Verona, Italy)
779 | Impact of dopamine receptor D2 on immune cells – driven synaptic alterations in multiple sclerosis
Alice Tartacca (University of Rome Tor Vergata – Rome, Italy)
783 | Neurofilament light chain levels quantified by Simoa® and Lumipulse™: a comparative study
Vanessa Chiodega (University of Verona – Verona, Italy)
787 | Integrated analysis of transcriptomic studies identifies shared molecular signatures and therapeutic targets in MS white matter pathology
Gianmarco Abbadessa (University of Campania Luigi Vanvitelli – Naples, Italy/Imperial College London – London, UK)