Somatic APP gene recombination in Alzheimer’s disease: a new paradigm for neuroscience and molecular biology.
The cells characterizing healthy metazoa bodies are meant to share and maintain the same genome, with tissue diversity being originated by differential gene expression and alternative mRNA splicing during transcription. Few exceptions exist in this paradigm, the most prominent being that of B ant T cells, which are able to rearrange genomic DNA through somatic […]