Intestinal barriers protect against disease


Disfunctional intestinal barrier is considered a main trigger in the onset of several pathologies, including neurodegenerative and autoimmune disorders.



This synopsis, written by Sandra Citi on Science, summarizes the main roles of gut epithelial barrier, the main components of its cellular and molecular machinery and the outcomes of its impairment. In this same Science Issue, three papers (mentioned in the article) have been published that focus on the link between impairment of the epithelial barrier in the gut and inflammatory and immune pathologies.

Source: Science Vol. 359, Issue 6380

Original text (for registered users) 



Image modified from Konig et al. (Source